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TITULOS
OBTENIDOS. Licenciado en Ciencias Bioquímicas (1970) y Doctor en Ciencias
Bioquímicas, Orientación Bioquímica Clínica. Facultad de Ciencias Exactas,
Universidad Nacional de La Plata.
POSICION
ACTUAL
- Miembro
de la Carrera del Investigador del Consejo Nacional de Investigaciones
Científicas y Técnicas. Categoría: Investigador Principal
- Profesor
Titular Ordinario Dedicación Exclusiva. Cátedra: Inmunología. Facultad de
Ciencias Exactas, Universidad Nacional de La Plata.
LUGAR DE
TRABAJO
-
Cátedra de Inmunología. Facultad de Ciencias Exactas, U.N.L.P.
Calles 47 y 115 - (1900) La Plata. Tel (0221) 423-5333 int 45. Email
afossati@biol.unlp.edu.ar
-
Instituto de Estudios de la Inmunidad Humoral (IDEHU, UBA-CONICET).
Facultad de Farmacia y Bioquímica, UBA. Junín 956, 4o Piso. (1113) Capital
Federal. Tel. (011) 4964-8259/60 Int. 113. Fax: 4964-0024. Email afossati@ffyb.uba.ar
DIRECCION
DE TESIS APROBADAS: 11
TRABAJOS
CIENTIFICOS PUBLICADOS Y/O EN PRENSA EN REVISTAS NACIONALES E
INTERNACIONALES: 80
PUBLICACIONES EN TEXTOS: 5
COMUNICACIONES EN CONGRESOS, JORNADAS Y SIMPOSIOS NACIONALES: 97
INTERNACIONALES: 69
ORGANIZACION DE CURSOS DE POSGRADO: 19
PARTICIPACION EN EL DICTADO DE CURSOS DE POSGRADO: 66
DICTADO DE
SEMINARIOS Y CONFERENCIAS: 28
SUBSIDIOS
RECIBIDOS: CONICET, CIC, ANPCyT, Antorchas, UNLP, UBA, Ministerio de Salud
de la Nación.
PREMIOS Y
DISTINCIONES: "
"Xeme Grand
Concours International 1978". Academie Internationale de Lutece, París
Premio "Dr.
Leonardo Satz" 2002, Sociedad Argentina de Inmunología.
Premio
"Fundación Manzullo" 1998, Asociación Argentina de Zoonosis.
Premio
"Patricio Cossio", 1997, Fundación Cossio
Licenciado
en Ciencias Bioquímicas y Dr. en Bioquímica, Facultad de Ciencias Exacta,
UNLP.
Profesor
Adjunto Dedicación Exclusiva a cargo de Inmunología, Facultad de Ciencias
Exactas, UNLP. Investigador Principal del CONICET. Perfeccionamiento pos
doctoral: National Institute for Biologicals Standars and Control y St.
Bartholomew´s School of Medicine, Londres, Inglaterra; especialización en
obtención, caracterización y utilización de anticuerpos monoclonales.
Líneas de
investigación. Estudio de la respuesta inmune y desarrollo de métodos de
diagnóstico para enfermedades por intolerancias alimentarias y por
infección con Brucella. Desarrollo de vacunas subcelulares
Trabajos
Científicos publicados en Revistas Periódicas
1.
"A novel radioimmunometric approach to the assay of components of
human haemostasis assay of plasma fibrinopeptide a level". P.J.Gaffney,
F.Joe, M.Mahamoud, C.A.Fossati, M.Spitz. Thrombosis Research 19, 815-822
(1980) pISSN: 0049-3848
2.
"Participation of Diffusible Products in the in vivo Immune
Primary Response to Red Blood Cells". C.A.Fossati, M.Spitz. Immunology 44,
11-15 (1981)
pISSN: 0019-2805
3.
"Anticuerpos Homogéneos Obtenidos por Fusión de Células Somáticas.
Hibridomas". C.A.Fossati, R.A.Margni. Revista Asociación Bioquímica
Argentina 46, 48-58 (1982)
4.
"Antibodies to poliovirus detected by immuno-radiometric assay with
a monoclonal antibody". M.Spitz, C.A.Fossati, G.C.Schild, L.Spitz,
M.Brasher. Journal of Virological Methods 5, 101-111 (1982)
pISSN:
0166-0934
5.
"Factores difusibles como activadores de la respuesta inmune
primaria in vivo". C.A.Fossati. Medicina (Buenos Aires) 43, 63-68
(1983) pISSN: 0025-7680
6.
"Anticuerpos Monoclonales como Reactivos de Laboratorio".
C.A.Fossati. Revista Argentina de Microbiología 15, 57-64 (1983). pISSN
0325-7541
7.
"Reacciones de Precipitación Mediante Mezcla de Anticuerpos
Monoclonales Dirigidos contra Diferentes Determinantes Isotípicos de IgG
Humana". C.A.Fossati. Inmunología 4, 146-150 (1985) pISSN 0213-9626
1988
8.
"Chromatofocusing:
a useful method for murine IgG1 monoclonal antibody purification".
L.Morelli,
J.R.Ronco, J.Leoni, C.A.Fossati. Comunicaciones Biológicas 7, 27-37 (1988)
9.
"Symmetric and Asymmetric IgG Antibodies are Synthesized by the
same Cellular Clone". L.Morelli, J.Leoni, C.A.Fossati, R.A.Margni.
Molecular Immunology 26, 789-792 (1989) pISSN: 0161-5890
10.
"Anticuerpos Monoclonales contra Antígenos de Posible Utilidad
Diagnóstica en Brucelosis Humana". L.Morelli, C.P.Rubbi, F.A.Goldbaum,
C.A.Fossati. Acta Bioquímica Clínica Latinoamericana 23, 309-314 (1989)
pISSN 0325-2957
11.
"Isolation of a Trypanosoma cruzi Antigen by Affinity
Chromatography with a Monoclonal Antibody. Preliminary Evaluation of its
Possible Aplications in Serological Test". C.H.Carbonetto, E.L.Malchiodi,
M.Chiaramonte, E.D. de Isola, C.A.Fossati, R.A.Margni. Clinical and
Experimental Immunology 82, 93-96 (1990)
pISSN:
0009-9104
12.
"Human brucellosis: immunoblotting analysis of three brucella
abortus antigenic fractions allows the detection of components of
diagnostic importance". F.A.Goldbaum, Laura Morelli, J.Wallach, C.P.Rubbi,
C.A.Fossati. Medicina 51, 227-232 (1991)
13.
"Differentiation Between Active and Inactive Human Brucellosis by
Measuring Antiprotein Humoral Immune Response". F.A.Goldbaum, C.P.Rubbi,
J.E.Wallach, S.E.Miguel, P.C.Baldi and C.A.Fossati. Journal of Clinical
Microbiology, 30, 604-607 (1992) pISSN: 0095-1137
14.
"Caracterización de un Antígeno de Trypanosoma cruzi
Purificado con Anticuerpos Monoclonales: Utilidad Diagnóstica y Análisis
de su Inmunogenicidad".
N.W.
Zwirner, E.L. Malchiodi, M.G. Chiaramonte, R.A. Margni, M. Esteva, C.A.
Fossati.
Inmunología 11, 120-127 (1992)
0213-9626
15.
"Analysis of oligosaccharides involved in asymmetrical
glycosylation of IgG monoclonal antibodies". L.Morelli, L.Plotkin, J.Leoni,
C.A.Fossati, R.A.Margni. Molecular Immunology 7, 695-700 (1993). pISSN:
0009-9104
16.
"Characterization of a 18 Kda Brucella Cytoplasmic Protein
Which Appears To Be a Serological Marker Of Active Infection of Both Human
and Bovine Brucellosis". F.A. Goldbaum, J. Leoni, J.C. Wallach, C.A.
Fossati. Journal of Clinical Microbiology 31, 2141-2145 (1993)
pISSN: 0095-1137
17.
"Urban Outbreak of Brucella melitensis Infection in an
Argentine Family: Clinical and Diagnostic Aspects". J.C.Wallach,
S.E.Miguel, P.C.Baldi, E.Guarnera, F.A.Goldbaum, C.A.Fossati. FEMS Immunol.
and Med. Microbiol. 8, 49-56 (1994).
pISSN: 0928-8244
18.
"Removal of LPS from a Brucella cytoplasmic fraction by affinity
chromatography with an anti-LPS monoclonal antibody as immunosorbent". F.A.
Goldbaum, C.P. Rubbi, C.A. Fossati. Journal of Medical Microbiology 40,
174-178 (1994)
pISSN:
0022-2615
19.
"A lytic Monoclonal Antibody to Trypanosoma cruzi
Bloodstream Trypomastigotes Which Recognizes an Epitope Expressed in
Tissues Affected in Chagas' Disease". N.W. Zwirner, E.L. Malchiodi, M.
Chiaramonte, C.A.Fossati. Infection and Immunity 62, 2483-2489 (1994)
pISSN: 0019-9567
20.
"Brucella abortus cytoplasmic proteins used as antigens in
an ELISA potentially useful for the diagnosis of canine brucellosis".
P.C.Baldi, M.M.Wanke, M.E.Loza, C.A.Fossati. Veterinary Microbiology 41,
127-134 (1994) pISSN: 0378-1135
21.
"Fractionation Of Wheat, Barley And Rye Prolamins By Cation
Exchange FPLC". F.G. Chirdo, C.A. Fossati and M.C Añón. Journal
Agriculture and Food Chemistry 42, 2460-2465 (1994)
pISSN 0021-8561
22.
"Methachromatic effect in homologous groups of wheat, barley and
rye prolamines". F.G. Chirdo, C.A. Fossati, M.C. Añón. Journal of Food
Biochemistry 18, 185-197 (1995)
pISSN:
0145-8884
23.
"Serodiagnóstico de la brucelosis humana
por aglutinación directa. Problemas de interpretación de resultados
obtenidos con diferentes antígenos comerciales".
Baldi, P.C., Wallach J.C., Fossati C.A. Acta Bioquímica Clínica
Latinoamericana 29, 147-157 (1995) pISSN 0325-2957
24.
“Modulation of cardiac physiology by an anti-Trypanosoma cruzi
monoclonal antibody after interaction with myocardium”. Cremaschi G,
Zwirner N.W, Gorelik G, Malchiodi E.L, Chiaramonte M.G, Fossati C.A,
Sterin Borda L. FASEB Journal, 9 1482-1488 (1995) pISSN: 0892-6638
25.
“Optimization of a Competitive ELISA with Polyclonal Antibodies for
Quantification of Prolamins in Foods". Chirdo F.G., Añón M.C., Fossati
C.A. Food and Agricultural Immunology 7, 333-343 1995 pISSN
0954-0105
26.
"N-glycanase treatment of f(ab')2 derived from
asymmetric murine igg3 mab determines the adcquisition of
precipitating activity".
I. Mathov,
L. Plotkin, L. Squiquera, C.A. Fossati, R.A. Margni, J. Leoni.
Molecular Immunology 32, 1123-1130 (1995)
pISSN: 0161-5890
27.
“Serological cross reactivity between Brucella abortus and
Yersinia enterocolitica 0:9. A) Immunoblot analysis of the antibody
response to Brucella protein antigens in bovine brucellosis”. R.
Kittelberger, F.Hilbinik, M.F. Hansen, M. Penrose, G.W. de Lisle, J.J.
Letesson, B. Garin-Bastuji, J. Searson, C.A. Fossati, A. Cloeckaert, G.
Shurig. Veterinary Microbiology 47, 257-270 (1995)
pISSN:
0378-1135
28.
“Serological Follow-Up of Human Brucellosis by Measuring IgG
Antibodies Directed to Lipopolysacharide and Cytoplasmic Proteins of
Brucella Species”. P.C. Baldi, S.E. Miguel, C.A. Fossati, J.C Wallach.
Clinical Infectious Diseases 22, 446-455 (1996)
pISSN: 1058-4838
29.
"Identification of casein as the major allergenic and antigenic
protein of cow’s milk". Docena G.H., Fernández R., Chirdo F.G., Fossati
C.A. Allergy 51, 412-416 (1996) pISSN: 0105-4538
30.
“Humoral Immune Response against Lipopolysaccharide and Cytoplasmic
Proteins of Brucella abortus in Cattle Vaccinated with B.
abortus s19 or Experimentally Infected with Yersinia enterocolitica
Serotype 0:9”. Baldi, PC, Giambartolomei, GH, Goldbaum, FA, Abdón, LF.,
Velikovsky, A., Kittelberger, R. and Fossati, CA. Clinical and Diagnostic
Laboratory Immunology 3, 472-476 (1996)
pISSN:
1071-412X
31.
“Interspecies cross-reactivity of a monoclonal antibody directed
against wheat chloroplast fructose 1,6-biphosphatase”. K. Hagelin, R.
Rodriguez-Suarez, F. Katzen, R.A. Wolosiuk, P.C. Baldi, G.H.
Giambartolomei, C.A. Fossati, T. Dyer. Cellular and Molecular Biology 42,
673-682 (1996)
pISSN: 1381-1932
32.
“Influence of Thermal Treatment of Food on the Immunochemical
Quantification of Gliadin”. Rumbo M, Chirdo F.G., Fossati C.A.; Añón M.C.
Food and Agricultural Immunology 8, 195-203, (1996).
ISSN p0954-0105
33.
“Analysis of Structural Properties and Immunochemical Reactivity of Heat
Treated Ovalbumin”. M. Rumbo, F.G. Chirdo, C.A. Fossati, M.C. Añón.
Journal of Agriculture and Food Chemistry.
44, 3793-3798 (1996) pISSN 0021-8561
34.
“Desarrollo de un ELISA de alta detectabilidad y especificidad para
la cuantificación de gliadinas en alimentos destinados a enfermos
celíacos”. F.G. Chirdo, M.C. Añón, C.A. Fossati. Acta Bioquímica Clínica
Latinoamericana 30, 389-399 (1996) pISSN 0326-2957
35.
“Immunoblotting of Gliadins Separated by Acid PAGE. Analysis of
Electrotransference Conditions”. Rumbo M., Chirdo F.G., Añón M.C. ,
Fossati C.A. Food and Agricultural Immunology 9, 135-139 (1997) pISSN
0954-0105
36.
“Characterization of Anti-Idiotypic Antibodies that Bind Antigen
and Anti-idiotype”. F.A. Goldbaum, C.A. Velikovsky, W. Dal’Acqua, C.A.
Fossati, R.A. Fields, B.C. Braden, R.J. Poljak, R.A Mariuzza. Proc. Natl.
Acad. Sci. U.S.A. 94, 8697-8701 (1997).
pISSN:
0027-8424
37.
“Diagnosis of canine brucellosis by detection of serum antibodies
against an 18 kDa cytoplasmic protein of Brucella spp.”. P.C. Baldi,
M.M. Wanke, M.E. Loza, N. Monachesi, C.A. Fossati. Veterinary Microbiology
57, 273-281 (1997)
pISSN:
0378-1135
38.
“Detection and characterization of antibodies specific to
food antigens (gliadin, ovoalbumin and
b-lactoglobulin) in human serum, saliva, colostrum and milk”. Rumbo, M.,
Chirdo, F.G., Añón, M.C. and
Fossati,
C.A. Clinical and Experimental Immunology 112 (3), 453-458 (1998). pISSN:
0009-9104
39.
“Development of High-sensitivity Enzyme Immunoassays for Gliadin
Quantification using the Streptavidin-Biotin Amplification System”. Chirdo,
F.G., Añón, M.C. and Fossati, C.A. Food and Agricultural Immnulogy 10 (2),
143-15 (1998)
.
ISSN
p0954-0105
40.
"Presence of High Levels of Non-Degraded Gliadin in Breast Milk
from Healthy Mothers". Chirdo F.G., Rumbo M., Añón M.C. and Fossati C.A.
Scandinavian Journal of Gastroenterology 33 (11): 1186-1192, (1998) pISSN:
0036-5521
41.
"Serological Investigation of Latex Allergy in Argentina." Docena
G., Fernández R., Ocampo M., Fossati C. Allergy and Asthma Proceedings 20
(2): 99-106 (1999)
pISSN: 1088-5412
42.
“Detection of allergens in Aedes Albifasciatus Mosquito (Diptera:
Culicidae) extracts by immunological methods”.
G H
Docena, P Benítez, R E Campos, A Macia, R Fernández, C A Fossati.
Journal
of Investigational Allergology & Clinical Immunology 9 (3): 165-171
(1999)
pISSN: 1018-9068
43.
"Preparative Fractionation of Gliadins by
Electrophoresis
At pH
3.1 (A-PAGE)".
M. Rumbo,
F.G. Chirdo, SA. Giorgeri, C.A. Fossati and M.C. Añón.
Journal
Agricultural and Food Chemistry. 47 (8), 3243-3247 (1999)
pISSN:
0021-8561
44.
“The 18 kDa Cytoplasmic Protein of Brucella species - an Antigen
Useful for Diagnosis - is a Lumazine Synthase”.
Goldbaum
FA, Velikovsky CA, Baldi PC, Mörtl S, Bacher A, Fossati CA.
Journal
of Medical Microbiology 48: 833-839 (1999)
pISSN:
0022-2615
45.
“Detection of Antibodies to Brucella Cytoplasmic Proteins in the
Cerebrospinal Fluid of Patients with Neurobrucellosis”.
Baldi PC,
Araj GF, Raccaro GC, Wallach JC, Fossati CA.
Clinical
and Diagnostic Laboratory Immunology 6 (5), 756-759 (1999)
pISSN:
1071-412X
46.
"Analysis of Anti-Gliadin Antibodies by Immunoblot Analysis and
Enzyme-Linked Immunosorbent Assay Using Gliadin Fractions As Antigens".
Fernando G. Chirdo, M. Rumbo, P. Carabajal, N. Castagnino, E.
Mavromatopulos, V. Cirincione, M. C. Añón and C. A. Fossati. Journal of
Pediatrics Gastroenterology and Nutrition.
29:
171-177 (1999) pISSN 0277-2116
47.
"Analysis of Anti-Prolamin Monoclonal Antibody Reactivity Using
Prolamin Fractions Purified by Preparative Electrophoresis". Rumbo M,
Chirdo F.G., Fossati, C.A., Añón M.C. Food and Agricultural Immunology 12:
41-52 (2000).
ISSN
p0954-0105
48.
"Identification of allergenic proteins in condoms by
immunoenzymatic methods". Docena G.H, Benítez P, Fernández R., Fossati
C.A. Annals of Allergy Asthma and Immunology 84: 77-83 (2000).
pISSN:
1081-1206
49.
"Structural, functional and immunological studies on a polymeric
bacterial protein". Baldi PC, Velikovsky CA, Braden BC, Giambartolomei GH,
Fossati CA, Goldbaum FA. Brazilian Journal of Medical and Biological
Research 33:741-747 (2000)
ISSN
0100-879X
50.
“Determination of Anti-w-Gliadin
Antibodies in Serological Test for Coeliac Disease”. Chirdo F.G., Rumbo
M., Carabajal P., Mavromatopulos E., Castagnino N., Añón M.C. and Fossati
C.A. Scandinavian Journal of Gastroenterology.
35: 508-516 (2000).
pISSN: 0036-5521
51.
“Determinación de anticuerpos contra proteínas citoplasmáticas de brucella
por ELISA para la detección de casos crónicos de brucelosis canina”.
Wanke MM, Monachesi NE, Loza ME, Rutter B, Baldi PC, Fossati CA.
Selecciones Veterinarias 8:308-311, 2000.pISSN 0327-859x
52.
"Single-shot plasmid DNA intrasplenic immunization for the
production of monoclonal antibodies. Persistent expression of DNA". C.A.
Velikovsky, J. Cassattaro, M. Sanchez, C.A. Fossati, L. Fainboim, M.
Spitz. Journal of Immunological Methods 244, 1-7 (2000)
pISSN:
0022-1759
53.
"Limited Diagnostic Usefulness of Antibodies to Cytoplasmic
Proteins of Brucella in Early-treated Human Brucellosis". Baldi PC,
Giambartolomei GH, Wallach JC, Velikovsky CA, Fossati CA. Scandinavian
Journal of Infectious Diseases 33 (3), 200-205 (2001)
pISSN:
0036-5548
54.
“Respuesta inmune dirigida contra antígenos proteicos de Brucella
spp. durante la infección experimental y la inmunización” Velikovsky CA,
Cassataro J, Giambartolomei GH, Baldi PC, Bowden R, Spitz M, Fossati CA.
Investigaciones Veterinarias, 3 (1-2): 193-196 (2001). ISSN 1514-6634
55.
“Analysis of the Effects of Heat Treatment on Gliadin
Immunodhemical Quantification Using a Panel of Anti-Prolamin Antibodies”.
M. Rumbo, F.G. Chirdo, C.A. Fossati, Añón M.C. Journal of Agricultural and
Food Chemistry,. 49: 5719-5726 (2001)
pISSN:
0021-8561
56.
“In vitro presentation of gliadin-derived peptides by different cell
lines”.
Chirdo F.G., Zwirner N.W., Rumbo M, Fossati C.A. Clinica Chimica Acta..
317(1-2): 151-158 (2002).
pISSN: 0009-8981
57.
“Evaluation of the residual antigenicity and allergenicity of cow’s
milk substitutes by in vitro tests”, Docena GH, Rozenfeld P,
Fernandez R And Fossati CA. Allergy 57: 83-91 (2002). pISSN
0105-4538
58.
“Diagnostic Usefulness of Antibodies Against Ribosome Recycling
Factor from Brucella melitensis in Human and Canine Brucellosis”.
J
Cassataro, MV Delpino, CA Velikovsky, L Bruno, CA Fossati, CP Baldi.
Clinical and Diagnostic Laboratory Immunology 9(2), 366-369 (2002). pISSN
1071-412X
59.
“Clinical and Diagnostic Aspects of Relapsing Meningoencephalitis
due to Brucella suis”.
J.C.
Wallach, P.C. Baldi, C.A. Fossati. Eur. J. Clin.
Microbiol Infect. Dis. 21, 760-762 (2002).
pISSN: 0934-9723
60.
“Immunogenicity of the Brucella melitensis recombinant ribosome
recycling factor-homologous protein and its cDNA”. J Cassataro, CA
Velikovsky, GH Giambartolomei, S Estein, L Bruno, A. Cloeakaert, RA
Bowden, M Spitz, CA Fossati,. Vaccine 20: 1660-1669 (2002)
pISSN:
0264-410X
61.
“Fractionation of secalins and hordeins by preparative
electrophoresis at acid pH”.
M. Rumbo,
AI Margheritis, FG Chirdo, SA Giorgeri, CA Fossati, MC Añón.
European
Food Research and Technology. 214: 198-201 (2002) pISSN 1438-2377
62.
"A DNA Vaccine Encoding Lumazine Sythase from Brucella abortus
Induces Protective Immunity in BALB/c Mice". Carlos A. Velikovsky, Juliana
Cassataro, Guillermo H Giambartolomei, Fernando A. Goldbaum, Silvia Estein,
Raul A. Bowden, Laura Bruno, Carlos A. Fossati and Moisés Spitz. Infection
and Immunity. 70(5):2507-2511 (2002)
pISSN:
0019-9567
63.
“Diminished Production of T Helper 1 Cytokines Correlates with
T-Cell Unresponsiveness to Brucella Cytoplasmic Proteins in Chronic
Human Brucellosis”. G.H. Giambartolomei, M.V. Delpino, M.E. Cahanovich,
J.C. Wallach, P.C. Baldi, C.A. Velikovsky, C.A. Fossati. Journal of
Infectious Diseases 186(2): 252-259 (2002)
pISSN: 0022-1899
64.
“Detection and identification of a soy protein component that cross-reacts
with caseins from cow milk”, Rozenfeld P, Docena GH, Añón MC, Fossati CA.
Clinical and Experimental Immunology, 130:49-58 (2002).
pISSN:
0009-9104
65.
“Antibodies to CP24 protein of Brucella melitensis lack
diagnosis usefulness in bovine brucellosis” M Victoria Delpino, Juliana
Cassataro, Carlos A. Fossati, Pablo C Baldi. Veterinary Microbiology 93,
101-107 (2003 pISSN: 0378-1135
66.
“Brucella Lumazine Snthase Elicits a Mixed TH1 TH2 Immune
Responseand Induce Protection in Mice Challenged with Brucella abortus
554 Independelntly of the Adjuvant Formulation Used” C.A. Velikovsky,
J. Cassataro, S. Estein, R.A. Bowden, L. Bruno. C.A. Fossati, G. H
Giambartolomei. Infection and Immunity 2003 Oct 71(10):5750-5755.
pISSN:
0019-9567
67.
“Antibody Reactivity to Omp31 from Brucella melitensis in Human
and Animal Infections by Smooth and Rough Brucellae”.
Cassataro J, Pasquevich K, Bruno L, Wallach JC, Fossati CA, Baldi PC.
Clinical and Diagnostic Laboratory Immunology. 2004; 11: 111-114.
pISSN:
1071-412X
68.
“Human
infection with the M- strain of Brucella canis.”
Wallach JC,
Giambartolomei GH, Baldi PC, Fossati CA.
Emerging
Infectious Diseases, 10:146-148 (2004) pISSN: 1080-6040
69.
“Engineering of a polymeric bacterial protein as a scaffold for the
multiple display of peptides”.
D. A.
Laplagne, V. Zylberman1, N. Ainciart, M. W. Steward, E. Sciutto, C. A.,
Fossati, F. A. Goldbaum.
PROTEINS:. 2004 Aug 18;57(4):820-828. pISSN:
0887-3585
70.
“Modulatory effects on myocardial physiology induced by an anti-Trypanosoma
cruzi monoclonal antibody involve recognition of major antigenic
epitopes from
b1-adrenergic
and M2-muscarinic cholinergic receptors without requiring receptor cross-linking”,
Graciela Cremaschi, Marisa M. Fernández, Gabriela Gorelik, Juan C. Goin,
Carlos A. Fossati, Norberto W. Zwirner and Emilio L. Malchiodi.
Journal
of Neuroimmunology . 2004 Aug;153(1-2):99-107. pISSN: 0165-5728
71.
.
“Occurrence and Potential Diagnostic Applications of Serological Cross-Reactivities
between Brucella and Other Alpha-Proteobacteria”.
M.
Victoria Delpino, Carlos A. Fossati, and Pablo C. Baldi.
Clinical
and Diagnostic Laboratory Immunology, Sept. 2004, p. 868–873
72.
“Lipoproteins, not Lipopolysaccharide, are the key mediators of the
proinflammatory response elicited by heat-killed Brucella abortus”,
Guillermo H. Giambartolomei, Astrid Zwerdling, Juliana Cassataro, Laura
Bruno, Carlos A. Fossati, and Mario T. Philipp.
J
Immunol. 2004 Oct 1;173(7):4635-42. pISSN: 0022-1767.
73.
“Serological prevalence of anti-latex IgE antibodies in unselected blood
donors in Argentina”.
Docena
GH, Fossati CA.
J Investig Allergol Clin Immunol. 2005;15(1):46-9. pISSN: 1018-9068
74.
“Development of an
immunochemical
method
to detect Lactobacillus kefir”.
GL Garrote,
MA Serradell, AG Abraham, MC Añón, CA Fossati, GL De Antoni.
Food and
Agricultural Immunology (2005) 16, 1-4; 221 - 233
pISSN
0954-0105
75.
“Mutation in the P36 gene of Mycobacterium bovis provokes attenuation of
the bacillus in a mouse model”. Bigi F, Gioffre A, Klepp L, Santangelo
MP, Velikovsky CA, Giambartolomei GH, Fossati CA, Romano MI, Mendum T,
McFadden JJ, Cataldi A .
Tuberculosis (Edinb). 2005 Jul;85(4):221-6. pISSN: 1472-9792
76.
“A DNA
vaccine coding for the Brucella outer membrane protein 31 confers
protection against B. melitensis and B. ovis infection by eliciting a
specific cytotoxic response”. Cassataro J, Velikovsky CA, de la Barrera S,
Estein SM, Bruno L, Bowden R, Pasquevich KA, Fossati CA, Giambartolomei GH
Infect Immun.
2005
Oct;73(10):6537-46. pISSN: 0019-9567
77.
“Vaccination with the
recombinant Brucella outer membrane protein 31 or a derived 27-amino-acid
synthetic peptide elicits a CD4+ T helper 1 response that protects against
Brucella melitensis infection”.
Cassataro J, Estein
SM, Pasquevich KA, Velikovsky CA, de la Barrera S, Bowden R, Fossati CA,
Giambartolomei GH. Infect Immun. 2005
Dec;73(12):8079-88. pISSN: 0019-9567
78.
“A
successful approach for the detection of Fabry patients in Argentina”.
Rozenfeld PA, Tarabuso A, Ebner R, Ramallo G, Fossati CA. A. Clin Genet
2006: 69: 344–348. pISSN: 0009-9163
79.
“Brucella
outer membrane protein Omp31 is a haemin-binding protein”. Delpino MV,
Cassataro J, Fossati CA, Goldbaum FA, Baldi PC.
Microbes
Infect. 8 (2006), 1203-1208. pISSN: 1286-4579
80.
"Immunofluorescence
Detection of Globotriaosylceramide (Gb3) Deposits in Conjunctival Biopsies
of Fabry Disease Patients".
Paula A Rozenfeld, Oscar Croxatto, Roberto Ebner, Carlos A. Fossati.
Clinical and Experimental Ophthalmology. 2006; 34:689-694 pISSN 0721-832X
81.
“A bile
salt hydrolase of Brucella abortus contributes to the establishment of a
successful infection through the oral route in mice.”
Delpino
MV,
Marchesini MI,
Estein SM,
Comerci
DJ,
Cassataro
J,
Fossati
CA,
Baldi PC.
Infect. Immun 2007 Jan; 75(1):299-305. Epub 2006 Nov 6.
pISSN: 0019-9567
82.
“Improved Immunogenicity of a Brucella DNA vaccine encoding Outer Membrane
Protein 31 (Omp31) by Recombinant Omp31 Boosting”.
Cassataro
J, Velikovsky CA, Bruno, L, Estein S, De la Barrera S, Bowden RA, Fossati
CA, Giambartolomei GH.
Clin Vaccine Immunol. 2007 Apr 11; [Epub ahead of print] pISSN
1556-6811
83.
“A
recombinant subunit vaccine based on the insertion of 27 amino acids from
Omp31 to the N-terminus of BLS induced a similar degree of protection
against B. ovis than Rev-1 vaccination.” Cassataro J, Pasquevich KA,
Estein SM , Laplagne D, Velikovsky CA, De la Barrera S, Bowden RA, Fossati
CA, Giambartolomei GH, Goldbaum FA.
Vaccine.
2007 May 30;25(22):4437-4446. Epub 2007 Apr 2. pISSN: 0019-9567
84.
“Hypogammaglobulinemia secondary to cow-milk allergy in children under 2
years of age”.
Liliana
Bezrodnik, Andrea Gómez Raccio, Laura Canil, Maria Amanda Rey, Patricia
Carabajal, Carlos Fosatti, Guillermo Docena.
Immunology. 2007 May 11; [Epub ahead of print] pISSN: 0019-2805
85.
“Partial Protection against Brucella Infection
in Mice by Immunization with Nonpathogenic Alphaproteobacteria” M.
Victoria Delpino, Silvia M. Estein, Carlos A. Fossati, and Pablo C.
Baldi1. Clinical and Vaccine Immunology, oct. 2007, p. 1296–1301
Trabajos
Publicados en Proceedings de Congresos
1.
"Efecto metacromático en proteínas derivadas de trigo, cebada y
centeno". F.G. Chirdo, C.E. Lupano, C.A. Fossati y M.C. Añon. Actas del
III Congreso Mundial de Tecnología de Alimentos. Barcelona (España), 20 al
23.02.91.
2.
"Desarrollo de un método inmunoquímico para la
cuantificación de prolaminas en alimentos". F.G. Chirdo, C.A. Fossati y
M.C. Añón. Actas VI Congreso Argentino de Ciencia y Tecnología de
Alimentos. Pág. 297-299. Buenos Aires, 06 al 08.04.94.
3.
"Producción de anticuerpos monoclonales anti-gliadinas".
F.G. Chirdo, C.A. Fossati y M.C. Añón. Actas VI Congreso Argentino de
Ciencia y Tecnología de Alimentos. Pág. 300-302. Buenos Aires, 06 al
08.04.94.
4.
“Análisis estructural y funcional de la proteína de 18 kDa
de Brucella spp, un marcador de infección brucelar activa”.
CA
Velikovsky, P Baldi, GC Racaro, CA Fossati, FA Goldbaum.
Boletín de
la Asociación Argentina
de Zoonosis, N° 8, (1998).
5.
“Characterization of anti-prolamin monoclonal antibody reactivity and
Development of high sensitive enzyme immunoassays for gliadin
determination”. Chirdo F.G., Rumbo M., Añón M.C. and Fossati C.A.
Proceeding del 13th Meeting of Working Group on Prolamin
Analysis and Toxicity.
Pag; 59-65.
Barcelona
(España), 05
al 08.11.98.
6.
“Diagnóstico y seguimiento de la brucelosis humana
mediante nuevos métodos serológicos”. J.C. Wallach, P.C. Baldi, F.A.
Goldbaum, C.A. Velikovsky, C.A. Fossati. Revista Argentina de
Microbiología, 31 (Supl. 1) 46-48 (1999)
7.
“Determinación de anticuerpos anti-proteínas para el
diagnóstico de la brucelosis en animales”. P.C. Baldi, F.A. Goldbaum, C.A.
Velikovsky, J.C. Wallach, C.A. Fossati. Revista Argentina de
Microbiología, 31 (Supl. 1) 49-51 (1999).
8.
"Effect of heat treatment on gliadin immunochemical quantification
in food". Rumbo M., Chirdo F.G., Añón M.C. and Fossati C.A. Proceeding of
the 14th Meeting of Working Group on Prolamin Analysis and Toxicity. Pag.
63-70. Stuttgart. Alemania. (1999).
9.
“Production of anti-human transglutaminase monoclonal antibodies” .
Chirdo F.G., Osman A.A., Mothes T., Rumbo M., Añón M.C. and Fossati C.A.
Proceedings of the 15th Meeting of Working Group on Prolamin Analysis and
Toxicity.
Pag. 173 - 176 Noviembre 8-12, 2000. Merano, Italia.
M. Stern Ed. Tubingen, Alemania.
10.
“Use of different standard solutions in gliadin immunochemical
quantification” . Rumbo M., Chirdo F.G., Barclay A., Margheritis A.,
Fossati C.A. and Añón M.C. Proceedings of the 15th Meeting of Working
Group on Prolamin Analysis and Toxicity.
Pag. 89 -95. Noviembre 8-12, 2000. Merano, Italia.
M. Stern Ed. Tubingen, Alemania.
11.
“Effect of reducing agents on the immunochemical quantification of
gliadins”. Margheritis A, Doña V, Fossati CA, Chirdo FG. Proceedings of
the 17th Meeting Working Group on Prolamin Analysis and
Toxicity. Pag. 65-70.Octubre 3-6, 2002. London, UK.. Ed. Stern M
Verlag Wissenchaftliche Scripten
2003
12.
“Interference of denaturing and reducing agents on gliadin/antibody
interaction.”.Doña V., Fossati C.A. and Chirdo F.G. Proceeding of the 18th
Meeting of the European Working Group on Prolamin Analysis and Toxicity.
2 al 5 de Octubre, 2003. Estocolmo.
Suecia. Ed. M. Stern.Verlag Wissenchaftliche Scripten 2004. pag 51-58
13.
Development of immunochemical and molecular biology tools for the study of
TG2 function and mapping function of the antibody reactivity in serum
samples”.
Bayardo M., Allegretti Y, Ferrara F., Di Niro R , Sblattero D and Chirdo
F.
Meeting of the European Working Group on Prolamin Analysis and Toxicity.
30/9 – 3/10 200419.
Praga, Rep. Checa. Ed. by M Stern,
Verlag Wissenchaftliche Scripten,
2005. pg. 117-122.
Trabajos
Científicos publicados en Textos
1.
"Hibridomas y Anticuerpos Monoclonales". Inmunología e
Inmunoquímica: Fundamentos. Cuarta Edición. Capítulo 30,
Pág
559-570. Editor: R.A.Margni. Editorial Médica Panamericana. Buenos Aires,
1989. ISBN 950-06-1459-6
2.
“Brucelosis”. Jorge Carlos Wallach y Carlos Alberto Fossati.
Temas de
Patología Infecciosa. Capítulo 33, Pág. 266-273. Editor: Olindo A. Martino.
Colección.: Fundación A. J. Roemmers. Libreros
López
Editores,
1995.
3.
“Hibridomas y Anticuerpos Monoclonales”. F.A. Goldbaum y C.A.
Fossati. Inmunología e Inmunoquímica, Fundamentos. Quinta Edición.
Capítulo 37, Pág. 781-797. Editor: R.A.Margni. Editorial Médica
Panamericana. Buenos Aires, 1996. ISBN 950-06-1495-2
4.
"Diez Preguntas sobre Brucelosis Humana”.
J.C. Wallach, C.A.
Fossati, P.C. Baldi.
"Infectología para la práctica diaria III". Ed. Daniel
Stanboulian. Ediciones FUNCEI. Buenos Aires, 1998. ISBN 950-9848-10-7
5.
“Introducción a
la Inmunología: parte I” C.A. Fossati, F.G. Chirdo, G.H. Docena, M.
Rumbo. En: Separata 2004. “Fisiopatología
Endocrina:
Bioquímica y Métodos Diagnósticos”. Pág. 6-20. Dir. M.A. Pisarev y R.S.
Calandra. Coord. M.O. Suescun y G.J Juvenal. Montpellier División Delta.
Buenos Aires, Argentina. 2004. ISSN 1515-3878
6.
“Caracterización molecular de una proteína citosólica de
Brucella y evaluación de su utilidad en el diagnóstico e
inmunoprofilaxis de la brucelosis.” Goldbaum FA, Baldi PC, Velikovsky CA,
Giambartolomei GH, Wallach JC, Cassataro J, Spitz M, Fossati CA. En:
“Inmunología Molecular: Nuevas Fronteras de
la Medicina”. Capítulo 22, Pág 239-245. Editor G.A. Rabinovich.
Editorial Médica Panamericana , Buenos Aires, Argentina, 2004. ISBN
950-06-1868-0
7.
”Inmunoglobulinas” F.A. Goldbaum, F. G. Chirdo y C.A.
Fossati. “Introducción a
la
Inmunobiología” Capítulo 12. Pág 303-342. Editores Penimpede E, Stanchi O,
Gómez C. .Editorial de
la Universidad Nacional
de La Plata, La
Plata, Argentina, 2004. ISBN 950-34-0259-x
8.
“Immunochemical
Methods for Detection of Probiotics”. Analía G. Abraham, María
Serradell, Graciela L. Garrote, Alberto C. Fossati, and Graciela L. De
Anton. in “Probiotics in Food Safety an Human Health”. Eds. Prof. Ipek
Goktepe and Dr. Vijay Juneja. Taylor Francis Group. Book Division. Boca
Raton, Fl. USA. 2005 ISBN 1-57444-514-6
9.
“Brucella”. R.A. Bowden, P.C. Baldi, J. Cassataro, D.J.
Comerci, S. Estein, C.A. Fossati, G.H. Giambartolomei, F.A. Goldbaum, J.C.
Wallach. Brucella, en:
“Microbiología Veterinaria”. N.O. Stanchi y col. (Editores). Editorial
Inter Médica.Buenos Aires Capítulo 39, pp. 281-293. 2007. ISBN
978-950-555-321-1
10.
“Respuesta inmune: Anticuerpos, alergias, vacunas y
reproducción humana”. A. Cauerhff, G. Docena, C. Fossati, F. Goldbaum.
Catálogo: Ciencias Naturales y Exactas. Colección: Colección Ciencia
Joven.
Editorial: EUDEBA (2006), Buenos Aires, ISBN : 950-23-1482-4
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